The present invention relates to a Lactuca sativa seed designated 41-26 RZ, which exhibits a combination of traits inclusing resistance against downy mildew races B1:1 to B1:28 and Ca-V to Ca-VIII, resistance against currant-lettuce aphid (Nasonovia ribisnigri) biotype Nr:0, resistance against Lettuce Mosaic Virus (LMV)), as well as medium green mature leaves with a hollow main vein. The present invention also relates to a Lactuca sativa plant produced by growing the 41-26 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 41-26 RZ.
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