Disclosed are methods and compositions for reducing E. coli O157:H7 colonization and shedding in ruminant animals. In certain aspects, methods are provided comprising delivering microencapsulated probiotic bacteria to the gastrointestinal tract of a ruminant animal. Microencapsulated probiotics for delivery to the gastrointestinal tract of a ruminant animal in order to reduce E. coli O157:H7 shedding are also provided.
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