A system, method and program product for enhancing individualized and safe food production using an iterative co-evolutionary approach. A system is disclosed that includes a production system for generating a set of end products based on an inputted set of host chromosomes and a parasite chromosome (which may include machine/human contaminants); an evaluation system for evaluating each end product; an evolution system for generating a set of evolved host chromosomes and an updated parasite chromosome; and a mechanism for generating a further set of end products based on the evolved host chromosomes and the updated parasite chromosome.
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